The global xerostomia therapeutics market size was valued at USD 650 million in 2021 and is projected to reach around USD 950 million in 2030 exhibiting a CAGR of 3.5% in the forecasted period. The rising adoption of chemotherapy and radiotherapy in cancer treatment coupled with increasing use of prescribed medications are some of the key factors projected to drive the market. Increase in the patients with diabetes around the globe impact the salivary glands. Also, consuming medicines can have a range of side effects where one of them is dry mouth. Therefore, people liable more and more and medicines are in a way backing to the growth of the xerostomia therapeutics market. Growing creativity and consciousness of the same is also endorsing the growth of the market. On the other hand, finger-prick autologous blood treatment, along with low level of awareness about the same in undersized nations can be a restraint in the growth of this market.
Chemotherapy and radiation harm the salivary gland and results in dry mouth. Chemotherapy is the most common form of treatment to cancer patients provided by oncologists and medical practitioners. According to the Centers for Disease Control & Prevention (CDC), each year around 650,000 cancer patients take chemotherapy in an outpatient oncology clinic. The American Cancer Society evaluates that 3.5 million women live with breast cancer in the U.S., as of January 1, 2016. Among women with stage IV breast cancer, 48% accept radiation and/or chemotherapy.
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Easy obtainability of cost-effective medicines is among the key drivers of the market. Products comprise saliva substitute gels, mouthwashes & oral rinses, sugar-free chewing gums, lozenges, toothpastes & oral-adhering discs, patches, and melts. The price of these products range from USD 10 to 90 and the reimbursement strategies of these products are favourable. For example, Ontario Ministry of Health and Long-Term Care provides funds to patients with radiation-induced xerostomia enduring treatment with drug, Salagen, in the Exceptional Access Program (EAP).
Upsurge in use of prescription medicines is projected to definitely disturb the market growth. As per the National Institute of Dental and Craniofacial Research, over 400 medicines may cause xerostomia. Prescription medicines such as antihypertensives, antidepressants, sedatives, antiparkinson, antiemetics, and antipsychotics distress the salivary gland and results in xerostomia. Growing prevalence of diseases such as hypertension, Parkinson’s disease, diabetes, and HIV lead to use of prescription drugs, thus instigating the state of dry mouth.
Market Segmentation:
By Type
• Artificial Saliva/Saliva Substitutes
• Salivary Stimulants
By Product
• Drugs
• Salivary Pens
• Other Product Types
By Distribution Channel
• Retail Pharmacies
• Hospital Pharmacies
• Online Pharmacies
Following are Top Key players Covered in Report:
• GlaxoSmithKline PLC
• Parnell Pharmaceuticals Inc.
• Bausch Health Companies Inc.
• 3M company
• Quest Products Inc.
• Fresenius SE & Co. KGaA
• Hikma Pharmaceuticals PLC
• Lupin Limited
• Sun Pharmaceutical Industries Ltd
• Sanofi (Chattem, Inc.)
• Synedgen Inc. (Prisyna)
• ADVANZ PHARMA Corp. Limited
• Saliwell Ltd
• Pharmascience Inc (Pendopharm)
• Other players
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Regional Analysis:
North America dominated the regional segment with the largest share of revenue followed by Europe. Key factors donating toward governance are growing prevalence of xerostomia and other dry mouth related diseases such as rheumatoid arthritis, Sjogren’s syndrome, and HIV combined with rise in dry mouth awareness initiatives. For example, Sjogren Syndrome Foundation of the U.S. is accountable for conducting awareness and assisting patients with xerostomia in the U.S. and Canada.
However, Asia Pacific is estimated to grow with a beneficial CAGR over the forecast period owing to rising healthcare expenditure, rise in initiatives for raising awareness, and growing prevalence of diseases such as HIV, cancer, diabetes, & Parkinson’s disease that cause dry mouth situations. Cancer rates are increasing drastically in the Asia-Pacific region. For example, as per GLOBOCAN 2020, there were 9,386,454 new cases of cancer in Asia, and it is expected to reach 14,229,878 by 2040. Developing economies, such as China and India, have implemented both health and industrial policies to inspire the domestic production of cancer drugs, which is aiming to inferior therapy costs. Lower therapy costs along with growing awareness about cancer, are intending to higher adoption of chemotherapy and radiotherapy. The growing burden of cancer leads to better adoption of radiotherapy and chemotherapy, along with the dry mouth conditions associated with the treatments. Thus, this generates the need for therapeutics for considering xerostomia, which eventually boosts the market growth in the region.
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